Innovative Therapies

Cannabis Medicine 
 
Cannabis is by far the most effective treatment for Alzheimer’s that we tried – and we’ve tried everything available on the market since 2010: zyprexa, ativan, seroquel, depakote, trazadone, aricept and namenda! There’s NO risk of sudden death or risk of organ failure, like the other meds used (mostly off label) to treat Alzheimer’s (and/or related dementias) symptoms!

Dr. Ethan B. Russo, MD from the International Cannabis and Cannabinoid Institute sat down with us at TheEmeraldCup for some blunt talk about how #CannabisHelpsDementia

 
 

Read the entire article in Frontiers in Integrative Neuroscience  

“Cannabis Therapeutics and the Future of Neurology”

October 18, 2018

[FTA]”…Initial trials of herbal cannabis for AD have begun sporadically, with a more focused effort in a California nursing home (Hergenrather, 2017). Patients were treated with a variety of preparations: THC-predominant (2.5–30 mg/dose), CBD predominant, and THCA, mainly in tinctures and confections. Marked benefit was reported on neuroleptic drug sparing, decreased agitation, increased appetite, aggression, sleep quality, objective mood, nursing care demands, self-mutilation and pain control.

Based on its pharmacology (Russo and Marcu, 2017), cannabis components may provide myriad benefits on target symptoms in this complex disorder:

  • Agitation: THC, CBD, linalool
  • Anxiety: CBD, THC (low dose), linalool
  • Psychosis: CBD
  • Insomnia/Restlessness: THC, linalool
  • Anorexia: THC
  • Aggression: THC, CBD, linalool
  • Depression: THC, limonene, CBD
  • Pain: THC, CBD
  • Memory: alpha-pinene (Russo, 2011; Russo and Marcu, 2017) + THC
  • Neuroprotection: CBD, THC
  • Reduced Aβ plaque formation: THC, CBD, THCA

Thus, an extract of a Type II chemovar of cannabis (THC/CBD) with a sufficient pinene fraction would seem to be an excellent candidate for clinical trials (Lewis et al., 2018)…”

 
 
Dr. Russo was also recently interviewed for  Forbes

“Cannabis For Parkinson’s And Alzheimer’s Diseases – An Interview With Dr. Ethan Russo”

February 26, 2019

[FTA] “…The best results in PD were reported in a Czech study in 2004, in which patients ate raw leaves of cannabis for as much as three months and reported significant improvement in overall function, tremor, bradykinesia and rigidity, with few side effects…

The story in AD is even more intriguing. Both THC and CBD have been shown to interfere with the production of abnormal toxic matter in the brain of such patients. This is quite exciting, inasmuch as synthetic drugs designed for similar purposes have yet to advance in the clinic. Both THC and particularly CBD are known neuroprotective agents that hold the potential to slow or perhaps even halt the degenerative process. On the symptom side, THC as a single agent has proven beneficial in AD patients in reducing nocturnal agitation, improving sleep and appetite. Observations of nursing home patients in California with dementia have produced similar benefits as well as reducing the need for nursing intervention and amounts of other drugs…”

Cannabis gave Mom clarity, calm, joy & a laissez faire attitude about losing her mind! 
 
Cannabis made her “now” more satisfying and helped her communicate with us more easily. It helped us focus on the skills that mom still had remaining, and to make the best of what was happening. 
 
Cannabis oil for behavioral issues. You can put it in food, a cookie, etc. 
 
Israel has been researching cannabis for 50 years. They use cannabis in all of their nursing homes. 
 
NiaMedic is an Israeli based health clinic with offices in OC and BH. 
 
They specialize in treating seniors and transitioning their patients on to cannabis medicine. First visit is $350 and includes 4 weeks of telephone follow ups once a week.

FYI: 

US PATENT #6630507B1 

Cannabinoids as antioxidants and neuroprotectants 

“Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism. This new found property makes cannabinoids useful in the treatment and prophylaxis of wide variety of oxidation associated diseases, such as ischemic, age-related, inflammatory and autoimmune diseases. The cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease and HIV dementia…”

 
Years ago, when we had mom at home, the only resources available to us were books, folklore and a couple resources on Facebook, where we learned from each other: Green Oil Machine; and Cannabis Oil Success Stories. 
 
I always tried the medicine before giving to mom so that I knew what she would be getting. 
 
For my mom, we used cannabis oil 1:1 cbd:thc about 25mg 2-3x/day.
 
This kind of treatment is all trial and error but no amount of error can kill the patient.

Coconut Oil/Medium Chain Triglycerides (MCTs) 

“Alzheimer’s disease: what if there was a cure and nobody knew” 
by Dr. Mary Newport
The diseased brain doesn’t process glucose properly, but ketones are an alternate sugar that feeds the brain. 
 
One way to get ketones is by eating Medium Chain Triglycerides (most easily found in coconut fat) 
Coconut shake:
1 cup coconut milk
Favorite fruits, frozen 

Additional bit of coconut oil for good measure – to be sure enough fat is getting into the system
*Consider adding a teaspoon of cannabis oil

Use coconut oil 
3T 3x/day 
OR
1 cup Coconut milk 3x/day
Medium chain triglycerides in coconut fat convert to ketones in the liver and feed the brain. 
Dementia/Alz is sometimes referred to as diabetes type 3 by researchers – the glucose receptors seem to be turned off in the patient. 
Giving them coconut fat feeds the brain. 
My mom re-gained two years of skills in three days of coconut milk based protein shakes: one fro breakfast, lunch and dinner.